AChE-IN-30

• UNSPSC Description:

  AChE-IN-30 is an AChE inhibitor with an IC50 value of 4.4 μM. AChE-IN-30 has neuroprotective activity, and inhibits H2O2-induced apoptosis by suppressing intracellular ROS accumulation. AChE-IN-30 can be used for research of Alzheimer's disease[1].

• Target Antigen:

  Cholinesterase (ChE)

• Type:

  Reference compound

• Related Pathways:

  Neuronal Signaling

• Applications:

  Neuroscience-Neurodegeneration

• Field of Research:

  Neurological Disease

• Assay Protocol:

  https://www.medchemexpress.com/ache-in-30.html

• Solubility:

  10 mM in DMSO

• Smiles:

  NC1=CC=C(NC2=C(NC3CCN(CC4=CC=CC=C4)CC3)C(C2=O)=O)C=C1

• Molecular Weight:

  376.45

• References & Citations:

  [1]Wan D, et al. Design, Synthesis, and Biological Activity of Donepezil: Aromatic Amine Hybrids as Anti-Alzheimerss Drugs. ACS Omega. 2023 Jun 5;8(24):21802-21812.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  2937454-22-1