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RdRP-IN-7

CAT: 0804-HY-154990Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-154990Size:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
RdRP-IN-7 is a RNA-dependent RNA polymerase (RdRp) inhibitor that shows the inhibition of SARS-CoV-2 infection with an IC50 of 8.2 μM, an IC90 of 14.1 μM and an CC90 of 79.1 μM. RdRP-IN-7 can be used for antiviral research[1].
UNSPSC
12352005
Target
SARS-CoV
Type
Reference compound
Related Pathways
Anti-infection
Applications
COVID-19-anti-virus
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/rdrp-in-7.html
Solubility
10 mM in DMSO
Smiles
OC[C@@H]1[C@@H](O[Si](C)(C)C(C)(C)C)[C@H](O[Si](C(C)(C)C)(C)C)[C@](C2=CNN=N2)(C3=CC=C4C(N)=NC=NN34)C1
Molecular Formula
C26H45N7O3Si2
Molecular Weight
559.85
References & Citations
[1]Savio Cardoza, et.al.Multistep Synthesis of Analogues of Remdesivir: Incorporating Heterocycles at the C-1′Position. The Journal of Organic Chemistry 2023 88 (13), 9105-9122
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported