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RdRP-IN-4

CAT: 0931-T62812-01Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0931-T62812-01Size:25 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Target
Others, Influenza Virus
Related Pathways
Others, Microbiology/Virology
Bioactivity
RdRP-IN-4 (compound 11q) is an arylbenzohydrazide analogue, an orally active inhibitor of influenza A virus RNA-dependent RNA polymerase (RdRp) that directly binds the PB1 subunit of RdRp. RdRP-IN-4 inhibited H1N1 (A/PR/8/34) Flu A and Flu B strains (B/Lee/1940) in a dose-dependent manner with EC50 values of 53 nM and 20 nM, respectively. RdRP-IN-4 had a significant antiviral effect in infected mice.
Molecular Formula
C17H17Br2N3O2
Molecular Weight
455.14
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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