RdRP-IN-8
CAT:
804-HY-162793
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
RdRP-IN-8
- UNSPSC Description: RdRP-IN-8 (compound 45) is an anti-influenza virus compound. RdRP-IN-8 inhibits viral RNA-dependent RNA polymerase (RdRP) activity by disrupting heterodimerization of PA and PB1 subunits (EC50=0.13 μM)[1].
- Target Antigen: Influenza Virus
- Type: Reference compound
- Related Pathways: Anti-infection
- Field of Research: Infection
- Assay Protocol: https://www.medchemexpress.com/rdrp-in-8.html
- Smiles: O=C(C1=C(O)C=C([N+]([O-])=O)C=C1)NC(S2)=C(C(NC3=CC=CC=C3O)=O)C4=C2CCCCC4
- Molecular Weight: 467.49
- References & Citations: [1]Bonomini, et al. "Optimization of Potent, Broad-spectrum, and Specific Anti-influenza Compounds Targeting RNA Polymerase PA-PB1 heterodimerization." European Journal of Medicinal Chemistry (2024): 116737.
- Shipping Conditions: Room temperature
- Clinical Information: No Development Reported