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RdRP-IN-9

CAT: 0931-T204421-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0931-T204421-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
1101848-34-3
Target
SARS-CoV
Related Pathways
Microbiology/Virology
Bioactivity
RdRP-IN-9 (Compound 6b) is a reversible covalent allosteric inhibitor of RdRp, demonstrating substantial anti-coronavirus activity with an EC50 of 0.68 μM against HCoV-OC43. By reversibly acylating the Cys12 in the NiRAN domain of non-structural protein 12 (nsp 12), it exerts prolonged antiviral effects and shows synergistic anti-coronavirus activity with Molnupiravir.
Smiles
O(C(CC)=O)[C@H]1[C@@]2([C@@]3(N(CC=4C2=CC5=C(C4)OCO5)CCC3=C[C@@H]1O)[H])[H]
Molecular Formula
C19H21NO5
Molecular Weight
343.374
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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