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PROTAC HDAC8 Degrader-4

CAT: 0013-GTR19277061-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19277061-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
PROTACHDAC8 Degrader-3 (Compound BP6) is an efficient and selective HDAC8PROTAC degrader with low cytotoxicity, exhibiting a DC50 of 80 nM. It demonstrates IC50 values of 0.26 μM for HDAC8 and 30 μM for CRBN. PROTACHDAC8 Degrader-3 enhances Ac-SMC3 levels, stabilizes p53, and sensitizes cells to targeted agents such as Idasanutlin, indicating significant potential for combination therapy.
Storage Conditions
-20°C
Notes
For research use only.

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