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PARP-2-IN-2

CAT: 0804-HY-151624Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-151624Size:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
PARP-2-IN-2 (compound 27) is a PARP 2 inhibitor with an IC50 value of 0.057 μM. PARP-2-IN-2 induces cell cycle arrest and apoptosis of MCF-7 breast cancer cells. PARP-2-IN-2 can be used for the research of cancer[1].
CAS Number
2915651-00-0
UNSPSC
12352005
Target
Apoptosis; PARP
Type
Reference compound
Related Pathways
Apoptosis; Cell Cycle/DNA Damage; Epigenetics
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/parp-2-in-2.html
Solubility
10 mM in DMSO
Smiles
O=C(NC1=CC=C(C2=NC3=CC(Cl)=CC=C3O2)C=C1)CCN(CC)CC
Molecular Formula
C20H22ClN3O2
Molecular Weight
371.86
References & Citations
[1]El-Ghobashy NM, et al. Synthesis, biological evaluation, and molecular modeling studies of new benzoxazole derivatives as PARP-2 inhibitors targeting breast cancer. Sci Rep. 2022 Sep 28;12 (1) :16246.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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