PARP-1/2/7-IN-1

PARP-1/2/7-IN-1

• CAS Number: 3034665-49-8
• UNSPSC Description: PARP-1/2/7-IN-1 (compound 86) is a potent inhibitor of PARP-1/2/7, with the IC50 of [1].
• Target Antigen: PARP
• Type: Reference compound
• Related Pathways: Cell Cycle/DNA Damage;Epigenetics
• Applications: Cancer-programmed cell death
• Field of Research: Cancer
• Assay Protocol: https://www.medchemexpress.com/parp-1-2-7-in-1.html
• Smiles: O=C1NN=C2C(CC[C@H]2N3C[C@H](C(N4CCN(C5=NC=C(C(F)(F)F)C=N5)CC4)=O)OCC3)=C1C(F)(F)F
• Molecular Weight: 547.45
• References & Citations: [1]Azkarra Therapeutics, Inc.; Oregon Health, et al. Preparation of pyridazin-3(2H)-one and pyridin-2(1H)-one PARP inhibitor compounds. World Intellectual Property Organization, WO2024073133 A1 2024-04-04
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported