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PARP/EZH2-IN-2

CAT: 0013-GTR19261813-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19261813-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
PARP/EZH2-IN-2 (compound 12e) functions as a dual inhibitor targeting both PARP1 and EZH2, with IC50 values of 6.89 and 27.34 nM, respectively. This compound exhibits anticancer activity without toxicity to normal cells, achieving synthetic lethality indirectly by increasing PARP1 sensitivity through EZH2 inhibition, and inducing cell death by modulating excessive autophagy.
Field of Research
Epigenetics & Chromatin, Molecular Biology
Molecular Formula
C33H31N7O3
Storage Conditions
-20°C
Notes
For research use only.

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