BChE-IN-13

• Description:

  BChE-IN-13 (Compound 17c) is an orally active, potent and selective Butyrylcholinesterase (BChE) inhibitor with IC50s of 0.22 and 0.016 μM for eqBChE and hBChE, respectively. BChE-IN-13 can improve memory and cognitive impairments, and be used in Alzheimer’s disease (AD) research[1].

• UNSPSC:

  12352005

• Target:

  Cholinesterase (ChE)

• Type:

  Reference compound

• Related Pathways:

  Neuronal Signaling

• Applications:

  Neuroscience-Neurodegeneration

• Field of Research:

  Neurological Disease

• Assay Protocol:

  https://www.medchemexpress.com/bche-in-13.html

• Solubility:

  10 mM in DMSO

• Smiles:

  O=C(NC1=CC=CC=C1C)CN(CC(C)C)CC2=CC=C3C=CC=CC3=C2

• Molecular Formula:

  C24H28N2O

• Molecular Weight:

  360.49

• References & Citations:

  [1]Xin Lu, et al. Design, synthesis, and biological evaluation of aromatic tertiary amine derivatives as selective butyrylcholinesterase inhibitors for the treatment of Alzheimer's disease.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• CAS Number:

  [2700896-73-5]