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TRK-IN-22

CAT: 0804-HY-150258Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-150258Size:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
TRK-IN-22 (compound 11) is a TRK inhibitor. TRK-IN-22 (compound 11), a typical type I inhibitor, covers the ATP-binding pocket of TRKA[1].
UNSPSC
12352005
Target
Trk Receptor
Type
Reference compound
Related Pathways
Neuronal Signaling; Protein Tyrosine Kinase/RTK
Applications
Cancer-Kinase/protease
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/trk-in-22.html
Solubility
10 mM in DMSO
Smiles
FC1=CC(CNC2=C(C=NC(NC3=CC=CC=C3)=N2)Cl)=CC=C1
Molecular Formula
C17H14ClFN4
Molecular Weight
328.77
References & Citations
[1]Tianxiao Wu , et al. Rational drug design to explore the structure-activity relationship (SAR) of TRK inhibitors with 2,4-diaminopyrimidine scaffold. Eur J Med Chem. 2022 Feb 15;230:114096.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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