TRK-IN-22
CAT:
804-HY-150258
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
TRK-IN-22
- UNSPSC Description: TRK-IN-22 (compound 11) is a TRK inhibitor. TRK-IN-22 (compound 11), a typical type I inhibitor, covers the ATP-binding pocket of TRKA[1].
- Target Antigen: Trk Receptor
- Type: Reference compound
- Related Pathways: Neuronal Signaling;Protein Tyrosine Kinase/RTK
- Applications: Cancer-Kinase/protease
- Field of Research: Others
- Assay Protocol: https://www.medchemexpress.com/trk-in-22.html
- Solubility: 10 mM in DMSO
- Smiles: FC1=CC(CNC2=C(C=NC(NC3=CC=CC=C3)=N2)Cl)=CC=C1
- Molecular Weight: 328.77
- References & Citations: [1]Tianxiao Wu , et al. Rational drug design to explore the structure-activity relationship (SAR) of TRK inhibitors with 2,4-diaminopyrimidine scaffold. Eur J Med Chem. 2022 Feb 15;230:114096.
- Shipping Conditions: Room temperature
- Clinical Information: No Development Reported