Products for Research Use Only
RegisterLogin

TRK-IN-27

CAT: 0804-HY-161179Size: 1 EachDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0804-HY-161179Size:1 Each
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
TRK-IN-27 (Compound 14q) is a potent TRK inhibitor with good kinase selectivity. TRK-IN-27 effectively inhibits tumor growth[1].
UNSPSC
12352005
Target
Trk Receptor
Type
Reference compound
Related Pathways
Neuronal Signaling; Protein Tyrosine Kinase/RTK
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/trk-in-27.html
Solubility
10 mM in DMSO
Smiles
FC1=C(Cl)C([C@H](NC2=CNC(C(C(NC3=CC=C(CN4CCN(C)CC4)C=C3)=O)=C2)=O)C)=C(Cl)C=C1
Molecular Formula
C26H28Cl2FN5O2
Molecular Weight
532.44
References & Citations
[1]Xu Z, et al. Discovery, Optimization, and Evaluation of Novel Pyridin-2 (1H) -one Analogues as Potent TRK Inhibitors for Cancer Treatment. J Med Chem. 2024 Jan 25;67 (2) :1168-1183.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

Related Products

CatalogName
HY-144451TRK-IN-12
HY-160166TRK-IN-26
HY-146521TRK-IN-15
HY-12327Trk-IN-1
HY-144423Trk-IN-10
HY-146519TRK-IN-14
HY-160165TRK-IN-25
HY-161819TRK-IN-29
HY-146522TRK-IN-16
HY-150561Trk-IN-20

Alternative Products

CatalogName
GTR19261676-01TRK-IN-27
PA1321-STrk-A
338192-01Trk A
T212244-01TRK-IN-32
T211064-01TRK-IN-31
T210169-01TRK-IN-29
T209555-01TRK-IN-22
T87568-01TRK-IN-25
T34958-01TRK-380
T63346-01TRK-IN-18

Popular Products