TRK-IN-31

• Target:

  Trk receptor

• Related Pathways:

  Tyrosine Kinase/Adaptors

• Bioactivity:

  TRK-IN-31 is an orally active TRK inhibitor with an IC50 of 1.8 nM. It demonstrates excellent antiproliferative activity in Ba/F3-MPRIP-TRKAG667C cells and selectively inhibits TRK kinase activity effectively. TRK-IN-31 also significantly suppresses tumor growth in a Ba/F3-MPRIP-TRKAG667C subcutaneous tumor mouse model.

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C