LSD1-IN-25

LSD1-IN-25

• CAS Number: 2911585-60-7
• UNSPSC Description: LSD1-IN-25 (Compound 9j) is a potent, selective and orally active LSD1 inhibitor with an IC50 of 46 nM (Ki = 30.3 nM). LSD1-IN-25 induces cancer cell apoptosis[1].
• Target Antigen: Apoptosis; Histone Demethylase
• Type: Reference compound
• Related Pathways: Apoptosis;Epigenetics
• Applications: Cancer-programmed cell death
• Field of Research: Cancer
• Assay Protocol: https://www.medchemexpress.com/lsd1-in-25.html
• Solubility: 10 mM in DMSO
• Smiles: ClC1=CC=CC(CN2C(N=C(SCCC)N=C3OC4=C(OC)C=C(CN[C@H]5C[C@@H]5C6=CC=CC=C6)C=C4OC)=C3N=N2)=C1
• Molecular Weight: 617.16
• References & Citations: [1]Li Z, et al. Design, synthesis and in vitro/in vivo anticancer activity of tranylcypromine-based triazolopyrimidine analogs as novel LSD1 inhibitors. Eur J Med Chem. 2023 May 5;253:115321.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported