MTHFD2-IN-3

CAT:

804-HY-149827

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UNSPSC Description: MTHFD2-IN-3 (compound 10) is a potent methylenetetrahydrofolate dehydrogenase (MTHFD2) inhibitor[1].
Target Antigen: Methylenetetrahydrofolate Dehydrogenase (MTHFD)
Type: Reference compound
Related Pathways: Metabolic Enzyme/Protease
Applications: Cancer-programmed cell death
Field of Research: Cancer
Assay Protocol: https://www.medchemexpress.com/mthfd2-in-3.html
Solubility: 10 mM in DMSO
Smiles: CS(=O)(CC1=CC=CC2=C1OC(C3=C2CCN(C3)C(C4=CC=C(C=C4)C(O)=O)=O)=O)=O
Molecular Weight: 441.45
References & Citations: [1]Jha V, et al. Binding Analysis and Structure-Based Design of Tricyclic Coumarin-Derived MTHFD2 Inhibitors as Anticancer Agents: Insights from Computational Modeling. ACS Omega. 2023 Apr 12;8(16):14440-14458.
Shipping Conditions: Room temperature
Clinical Information: No Development Reported

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