MTHFD2-IN-1

CAT:

804-HY-149825

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UNSPSC Description: MTHFD2-IN-1 (compound 12) is a potent methylenetetrahydrofolate dehydrogenase (MTHFD2) inhibitor[1].
Target Antigen: Methylenetetrahydrofolate Dehydrogenase (MTHFD)
Type: Reference compound
Related Pathways: Metabolic Enzyme/Protease
Applications: Cancer-programmed cell death
Field of Research: Cancer
Assay Protocol: https://www.medchemexpress.com/mthfd2-in-1.html
Solubility: 10 mM in DMSO
Smiles: O=C(C1=CC=C(C=C1)C(N2CCC3=C(C(OC4=C3C=CC=C4C5CC(C5)O)=O)C2)=O)O
Molecular Weight: 419.43
References & Citations: [1]Jha V, et al. Binding Analysis and Structure-Based Design of Tricyclic Coumarin-Derived MTHFD2 Inhibitors as Anticancer Agents: Insights from Computational Modeling. ACS Omega. 2023 Apr 12;8(16):14440-14458.
Shipping Conditions: Room temperature
Clinical Information: No Development Reported

Cat	Name
HY-149825	MTHFD2-IN-1
HY-149827	MTHFD2-IN-3
HY-149828	MTHFD2-IN-4
HY-149826	MTHFD2-IN-2
HY-149828A	MTHFD2-IN-4 (sodium)
HY-RS08776	MTHFD2 Human Pre-designed siRNA Set A
HY-163546	HSV-1-IN-1
HY-163731-01	EGR-1-IN-1
HY-159569-04	TfR-1-IN-1
HY-159569-01	TfR-1-IN-1