MTHFD2-IN-4 (sodium)

MTHFD2-IN-4 (sodium)

• UNSPSC Description: MTHFD2-IN-4 sodium, tricyclic coumarin derivative, is a potent MTHFD2 inhibitor. MTHFD2-IN-4 sodium can be used in research of cancer[1].
• Target Antigen: Methylenetetrahydrofolate Dehydrogenase (MTHFD)
• Type: Reference compound
• Related Pathways: Metabolic Enzyme/Protease
• Applications: Cancer-programmed cell death
• Field of Research: Cancer
• Assay Protocol: https://www.medchemexpress.com/mthfd2-in-4-sodium.html
• Solubility: 10 mM in DMSO
• Smiles: O=C1OC2=C(C3=C1CN(CC3)C(C4=CC=C(C=C4)C(C(F)(F)F)(O[Na])C(F)(F)F)=O)C=CC(C5CNCCO5)=C2
• Molecular Weight: 578.44
• References & Citations: [1]Jha V, et, al. Binding Analysis and Structure-Based Design of Tricyclic Coumarin-Derived MTHFD2 Inhibitors as Anticancer Agents: Insights from Computational Modeling. ACS Omega. 2023 Apr 12;8(16):14440-14458.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported