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Bcl-2-IN-12

CAT: 0804-HY-149622Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-149622Size:1 Each
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Description
Bcl-2-IN-12 (Compound 1) is a Bcl-2 inhibitor (IC50: 6 nM) . Bcl-2-IN-12 can be used for cancer research[1].
CAS Number
1383737-59-4
UNSPSC
12352005
Target
Bcl-2 Family
Type
Reference compound
Related Pathways
Apoptosis
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/bcl-2-in-12.html
Solubility
10 mM in DMSO
Smiles
O=C(C1=CC=C(C2=C(CCCC)N(C3=CC=C(C=C3)OC4=CC(Cl)=CC=C4)N=C2CO)C(C(N5CC6=C(CC5)C=CC=C6)=O)=C1)NS(=O)(C7=CC8=C(C=CC=C8)C=C7)=O
Molecular Formula
C47H41ClN4O6S
Molecular Weight
825.37
References & Citations
[1]Ismail HS, et al. Design, molecular modelling and synthesis of novel benzothiazole derivatives as BCL-2 inhibitors. Sci Rep. 2023 Sep 20;13 (1) :15554.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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