Mtb-IN-3

• Description:

  Mtb-IN-3 (compound 10c) is an inhibitor of Mycobacterium tuberculosis (Mtb) . Mtb-IN-3 shows selective, potent in vitro antimycobacterial activity without cytotoxicity. Mtb-IN-3 inhibits colony-forming in spleen in the murine tuberculosis model[1].

• UNSPSC:

  12352005

• Target:

  Bacterial

• Type:

  Reference compound

• Related Pathways:

  Anti-infection

• Applications:

  COVID-19-immunoregulation

• Field of Research:

  Infection

• Assay Protocol:

  https://www.medchemexpress.com/mtb-in-3.html

• Solubility:

  10 mM in DMSO

• Smiles:

  O=C(C1=NC2=C(C=CC=C2)C=C1)NC(C=C3)=CC4=C3C(OCO4)=O

• Molecular Formula:

  C18H12N2O4

• Molecular Weight:

  320.30

• References & Citations:

  [1]Nawrot DE, et al. Antimycobacterial pyridine carboxamides: From design to in vivo activity. Eur J Med Chem. 2023 Oct 5;258:115617.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• CAS Number:

  [3052302-61-8]