Mtb-IN-13

• Description:

  Mtb-IN-13 (Compound 5f) is an inhibitor of Mycobacterium tuberculosis (Mtb), with a MIC of 0.25 μg/mL. The Ki values of MTTB-in-13 for MtCA1, MtCA2, MtC, and 3 are 0.6023, 0.0780, and 0.1994 μM, respectively. Mtb-IN-13 can be used in the research of tuberculosis[1].

• UNSPSC:

  12352005

• Target:

  Bacterial; Carbonic Anhydrase

• Related Pathways:

  Anti-infection; Metabolic Enzyme/Protease

• Applications:

  COVID-19-immunoregulation

• Field of Research:

  Infection

• Smiles:

  O=S (C1=CC=C (N2N=NC (COC3=CC4=C (N (C) C (C) =C4C (/C=C/C5=C (Cl) C=CC=C5Cl) =O) C=C3) =C2) C=C1) (N) =O

• Molecular Formula:

  C28H23Cl2N5O4S

• Molecular Weight:

  596.48

• References & Citations:

  [1]Singampalli A, et al. Exploring Indole-Linked Triazole Sulfonamide Derivatives as Potent Mycobacterial Carbonic Anhydrase Inhibitors: Leveraging a Tail Approach for the Design, Synthesis, and In Silico Studies─An In-Depth Multidisciplinary Study. J Med Chem. 2025 Sep 11;68 (17) :18370-18388.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported