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Mtb-IN-6

CAT: 0804-HY-157870Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-157870Size:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Mtb-IN-6 (Compound C10) is a Mycobacterium tuberculosis (Mtb) respiration inhibitor. Mtb-IN-6 can enhance the bactericidal activity of isoniazid (INH, HY-B0329). Mtb-IN-6 inhibits WT Mtb with an IC50 of 25 µM[1].
UNSPSC
12352005
Target
Bacterial
Type
Reference compound
Related Pathways
Anti-infection
Applications
COVID-19-immunoregulation
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/mtb-in-6.html
Solubility
10 mM in DMSO
Smiles
O=C(C1CSC2=C(C(CC3=CC=CC4=C3C=CC=C4)=CC(N21)=O)C5CCC5)O
Molecular Formula
C23H21NO3S
Molecular Weight
391.48
References & Citations
[1]Harrison GA, et al. Inducing vulnerability to InhA inhibition restores isoniazid susceptibility in drug-resistant Mycobacterium tuberculosis. mBio. 2024 Jan 31:e0296823.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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