Mtb-IN-6

• Description:

  Mtb-IN-6 (Compound C10) is a Mycobacterium tuberculosis (Mtb) respiration inhibitor. Mtb-IN-6 can enhance the bactericidal activity of isoniazid (INH, HY-B0329) . Mtb-IN-6 inhibits WT Mtb with an IC50 of 25 µM[1].

• UNSPSC:

  12352005

• Target:

  Bacterial

• Type:

  Reference compound

• Related Pathways:

  Anti-infection

• Applications:

  COVID-19-immunoregulation

• Field of Research:

  Infection

• Assay Protocol:

  https://www.medchemexpress.com/mtb-in-6.html

• Solubility:

  10 mM in DMSO

• Smiles:

  O=C(C1CSC2=C(C(CC3=CC=CC4=C3C=CC=C4)=CC(N21)=O)C5CCC5)O

• Molecular Formula:

  C23H21NO3S

• Molecular Weight:

  391.48

• References & Citations:

  [1]Harrison GA, et al. Inducing vulnerability to InhA inhibition restores isoniazid susceptibility in drug-resistant Mycobacterium tuberculosis. mBio. 2024 Jan 31:e0296823.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported