Mtb-IN-11

• Description:

  Mtb-IN-11 (Compound 1e) is an inhibitor of Mycobacterium tuberculosis salicylate synthase (MbtI), with an IC50 of 11.2 μM. Mtb-IN-11 exhibits good in vitro anti-tuberculosis activity, with a MIC99 of 32 μM against M. bovis BCG. Mtb-IN-11 can be used for the research of tuberculosis[1].

• UNSPSC:

  12352005

• Target:

  Bacterial

• Related Pathways:

  Anti-infection

• Field of Research:

  Infection

• Smiles:

  O=C(C1=CC=C(C2=CC(OCC(C)C)=CC(C#N)=C2)O1)O

• Molecular Formula:

  C16H15NO4

• Molecular Weight:

  285.29

• References & Citations:

  [1]Cazzaniga G, et al. Nanoenabling MbtI Inhibitors for Next-Generation Tuberculosis Therapy. J Med Chem. 2025 Mar 13;68 (5) :5312-5332.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported