BChE-IN-16

CAT: 0804-HY-149243Size: 1 EachDry Ice: NoHazardous: No
CAT#:0804-HY-149243Size:1 Each
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Description
BChE-IN-16 (compound 87) is a highly potent BChE inhibitor with an IC50 of 3.8 nM for hBChE. BChE-IN-16 has low cytotoxicity, potential CNS permeability, unique adaptability and can be used in Alzheimer's disease (AD) research.
UNSPSC
12352005
Target
Cholinesterase (ChE)
Type
Reference compound
Related Pathways
Neuronal Signaling
Applications
Neuroscience-Neurodegeneration
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/bche-in-16.html
Solubility
10 mM in DMSO
Smiles
COC1=CC=CC(CN(C2CCC2)CCCC3=C(C=CC=C3)F)=C1OCC4=CC=CC=C4
Molecular Formula
C28H32FNO2
Molecular Weight
433.56
References & Citations
[1]Pidany F, et al. Highly selective butyrylcholinesterase inhibitors related to Amaryllidaceae alkaloids - Design, synthesis, and biological evaluation. Eur J Med Chem. 2023 Apr 5;252:115301.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
BChE

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