Products for Research Use Only

MAO-B-IN-20

CAT: 0804-HY-149242Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-149242Size:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
MAO-B-IN-20 (Compound C14) is a potent MAO-B inhibitor with an IC50 of 0.037 μM. MAO-B-IN-20 displays good metabolic stability and brain-blood barrier permeability. MAO-B-IN-20 can be used for the research of Parkinson's disease[1].
UNSPSC
12352005
Target
Monoamine Oxidase
Type
Reference compound
Related Pathways
Neuronal Signaling
Applications
Neuroscience-Neurodegeneration
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/mao-b-in-20.html
Solubility
10 mM in DMSO
Smiles
NC([C@@H]1C[C@@H](CN1CC2=CC3=C(OC(C4=CC=C(C=C4)F)=C3)C=C2)F)=O
Molecular Formula
C20H18F2N2O2
Molecular Weight
356.37
References & Citations
[1]Yi C, et al. Design, synthesis and evaluation of novel monoamine oxidase B (MAO-B) inhibitors with improved pharmacokinetic properties for Parkinson's disease. Eur J Med Chem. 2023 Apr 5;252:115308.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
MAO-A; MAO-B