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MAO-B-IN-47

CAT: 0804-HY-W628136Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-W628136Size:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
MAO-B-IN-47 is a selective monoamine oxidase B (MAO-B) inhibitor with a Ki of 875 nM. MAO-B-IN-47 shows an IC50 >100 μM for SH-SY5Y cells. MAO-B-IN-47 shows neuroprotective effect in 6-OHDA-treated SH-SY5Y cells. MAO-B-IN-47 can be used for the research of neurological disease, such as Parkinson’s disease (PD) [1].
CAS Number
67082-01-3
UNSPSC
12352005
Hazard Statement
H302-H315-H319-H335
Target
Monoamine Oxidase
Related Pathways
Neuronal Signaling
Applications
Neuroscience-Neurodegeneration
Field of Research
Neurological Disease
Smiles
O=C(C1=CC(C(F)(F)F)=CC=C1)CCC2=CC=CC=C2
Molecular Formula
C16H13F3O
Molecular Weight
278.27
Precautions
P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
References & Citations
[1]Facchetti G, et al. Design, synthesis, and biological evaluation of chalcone derivatives as selective Monoamine Oxidase-B inhibitors with potential neuroprotective effects. Eur J Med Chem. 2025 Nov 15;298:117990.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
MAO-B

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