Products for Research Use Only
RegisterLogin

MAO-B-IN-48

CAT: 0804-HY-175523Size: 1 EachDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0804-HY-175523Size:1 Each
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
MAO-B-IN-48 is a selective MAO-B inhibitor (IC50 = 0.09 μM, Ki = 0.02 μM) . MAO-B-IN-48 exhibits inhibitory activity against hBChE (IC50 = 1.10 μM, Ki = 0.43 μM) and AChE (IC50 = 0.56 μM, Ki = 0.14 μM) . MAO-B-IN-48 suppresses self-induced aggregation of toxic β-amyloid peptides and exerts antioxidant activity, including DPPH radical scavenging, CUPRAC copper ion reduction, and superoxide anion scavenging. MAO-B-IN-48 can be used for the study of Alzheimer's disease (AD) [1].
UNSPSC
12352100
Target
Amyloid-β; Cholinesterase (ChE) ; Monoamine Oxidase
Related Pathways
Neuronal Signaling
Field of Research
Neurological Disease
Smiles
C[C@H](C1=CC=CC2=C1C=CC=C2)NC(OC3=CC(N(C)C)=CC=C3)=S
Molecular Formula
C21H22N2OS
Molecular Weight
350.48
References & Citations
[1]Teke Tuncel S, et al. Multitarget-directed carbamate and carbamothioate derivatives: Cholinesterase and monoamine oxidase inhibition, anti-β-amyloid (Aβ) aggregation, antioxidant and blood-brain barrier permeation properties against Alzheimer's disease. Eur J Med Chem. 2025 Nov 15;298:117986.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
AChE; BChE; MAO-A; MAO-B

Related Products

CatalogName
HY-W628136MAO-B-IN-47
HY-W207699MAO-B-IN-46
HY-149234-01MAO-B-IN-18
HY-146149MAO-B-IN-11
HY-168138MAO-B-IN-34
HY-143330MAO-B-IN-4
HY-146347MAO-B-IN-10
HY-151208MAO-B-IN-16
HY-151209MAO-B-IN-15
HY-149820MAO-B-IN-22

Alternative Products

CatalogName
GTR19264651-01MAO-B-IN-48
B2919-5MAO-A/MAO-B Inhibitor
YP-W19977-01Human MAO-B (MAO-B) ELISA Kit
YP-W200865-01Mouse MAO-B (MAO-B) ELISA Kit
YP-W35915-01Rat MAO-B (MAO-B) ELISA Kit
sc-515575MAO-B (B-8)
M37657-01MAO-B-IN-5
M35454-01MAO-B-IN-9
BA8520-25MAO-B-IN-2
T212299-01MAO-B-IN-46

Popular Products