NSC363998 (free base)

• UNSPSC Description:

  NSC363998 (free base) is an orally active compound. NSC363998 (free base) can suppress rCGG90 induced neurotoxicity. NSC363998 (free base) can be used for the research of neurodegenerative disorder such as Fragile X associated tremor/ataxia syndrome (FXTAS)[1].

• Target Antigen:

  Others

• Type:

  Reference compound

• Related Pathways:

  Others

• Applications:

  Neuroscience-Neuromodulation

• Field of Research:

  Neurological Disease

• Assay Protocol:

  https://www.medchemexpress.com/nsc363998-free-base.html

• Solubility:

  10 mM in DMSO

• Smiles:

  O=C1C2=C(C(C3=C1C(NCCCNCCO)=CC=C3)=O)C(NCCCNCCO)=CC=C2

• Molecular Weight:

  440.54

• References & Citations:

  [1]Yunting Lin, et al. Neddylation activity modulates the neurodegeneration associated with fragile X associated tremor/ataxia syndrome (FXTAS) through regulating Sima. Neurobiol Dis. 2020 Sep;143:105013.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  159357-82-1