EGFR-IN-63

CAT: 0804-HY-147967Size: 1 EachDry Ice: NoHazardous: No
CAT#:0804-HY-147967Size:1 Each
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Description
EGFR-IN-63 is an EGFR inhibition (IC50: 0.096 μM) and it has anticancer activity in MCF-7 cells (IC50: 2.49 μM) .
CAS Number
[2414635-72-4]
UNSPSC
12352005
Target
EGFR
Type
Reference compound
Related Pathways
JAK/STAT Signaling; Protein Tyrosine Kinase/RTK
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/egfr-in-63.html
Solubility
10 mM in DMSO
Smiles
BrC1=CC2=C(NC3=NC4=CC=CC=C4S3)N=C(C5=CC=CN=C5)N=C2C=C1
Molecular Formula
C20H12BrN5S
Molecular Weight
434.31
References & Citations
[1]Heba Abdelrasheed Allam, et al, Design and Synthesis of some new 2,4,6-trisubstituted quinazoline EGFR inhibitors as targeted anticancer agents, Bioorg Chem. 2020 May;98:103726
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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