α-Glucosidase-IN-63

• UNSPSC Description:

  α-Glucosidase-IN-63 (Compound 4d) is an inhibitor of α-Glucosidase (IC50=0.44 μM). α-Glucosidase-IN-63 inhibits hCA II with an activity of Ki= 7.0 nM. α-Glucosidase-IN-63 is orally effective.[1].

• Target Antigen:

  Carbonic Anhydrase; Glycosidase

• Type:

  Reference compound

• Related Pathways:

  Metabolic Enzyme/Protease

• Applications:

  Metabolism-sugar/lipid metabolism

• Field of Research:

  Endocrinology

• Assay Protocol:

  https://www.medchemexpress.com/α-glucosidase-in-63.html

• Solubility:

  10 mM in DMSO

• Smiles:

  O=S(C1=CC=C(/N=C(NC/2=O)/SC2=C\C3=CC=C(F)C=C3)C=C1)(N)=O

• Molecular Weight:

  377.41

• References & Citations:

  [1]Gamal MA, et al. Probing benzenesulfonamide-thiazolidinone hybrids as multitarget directed ligands for efficient control of type 2 diabetes mellitus through targeting the enzymes: α-glucosidase and carbonic anhydrase II. Eur J Med Chem. 2024 May 5;271:116434.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  2375866-82-1