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NLRP3-IN-63

CAT: 0804-HY-170532Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-170532Size:1 Each
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Description
NLRP3-IN-63 (Compound 7) is an inhibitor for NLRP3, that inhibits the NLRP3 activation with an EC50 of 13 nM[1].
CAS Number
3064696-02-9
UNSPSC
12352005
Target
NOD-like Receptor (NLR)
Type
Reference compound
Related Pathways
Immunology/Inflammation
Field of Research
Inflammation/Immunology; Neurological Disease
Assay Protocol
https://www.medchemexpress.com/nlrp3-in-63.html
Smiles
OC1=CC(C(F)(F)F)=CC=C1C2=C(C)C3=C(N([C@H]4CN(CC)CCC4)C=N3)N=N2
Molecular Formula
C20H22F3N5O
Molecular Weight
405.42
References & Citations
[1]SHARP M, et al., 5,6 UNSATURATED BICYCLIC HETEROCYLES USEFUL AS INHIBITORS OF NOD-LIKE RECEPTORPROTEIN 3. WO2024249539
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported