CB1R Allosteric modulator 2

• Description:

  CB1R Allosteric modulator 2 (compound 18) is a potent CB1R allosteric modulator. CB1R Allosteric modulator 2 shows negatively affects the functional activity of orthosteric ligands (NAM) at CB1Rs[1].

• UNSPSC:

  12352005

• Target:

  Cannabinoid Receptor

• Type:

  Reference compound

• Related Pathways:

  GPCR/G Protein; Neuronal Signaling

• Applications:

  Neuroscience-Neuromodulation

• Field of Research:

  Others

• Assay Protocol:

  https://www.medchemexpress.com/cb1r-allosteric-modulator-2.html

• Solubility:

  10 mM in DMSO

• Smiles:

  O=C (NC1=CC (NC2=CC=C (C=C2) F) =CC=C1) NC3=CC=C (C=C3) Cl

• Molecular Formula:

  C19H15ClFN3O

• Molecular Weight:

  355.79

• References & Citations:

  [1]Meini S, et al. PSNCBAM-1 analogs: Structural evolutions and allosteric properties at cannabinoid CB1 receptor. Eur J Med Chem. 2020 Oct 1;203:112606.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• Isoform:

  CB1

• CAS Number:

  2513102-64-0