GluN2A Allosteric modulator 1

• Target:

  IGluR

• Related Pathways:

  Neuroscience|||Membrane transporter/Ion channel

• Bioactivity:

  GluN2A Allosteric modulator 1 (Compound 11) is an orally bioavailable compound that effectively crosses the blood-brain barrier and functions as a highly selective negative allosteric modulator of GluN2A. It exhibits an IC50 of 0.042 ?M for GluN2A and 13 ?M for GluN2B. This compound is useful for research in neurological disorders.

• Smiles:

  ClC1=CC=CC (C (F) (F) COC2=NC=C (C (NC3 (C4=CN=CC=N4) CC3) =O) N=C2) =C1

• Molecular Formula:

  C20H16ClF2N5O2

• Molecular Weight:

  431.823

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C