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GluN2A Allosteric modulator 1

CAT: 0931-T205030-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0931-T205030-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Target
IGluR
Related Pathways
Neuroscience, Membrane transporter/Ion channel
Bioactivity
GluN2A Allosteric modulator 1 (Compound 11) is an orally bioavailable compound that effectively crosses the blood-brain barrier and functions as a highly selective negative allosteric modulator of GluN2A. It exhibits an IC50 of 0.042 μM for GluN2A and 13 μM for GluN2B. This compound is useful for research in neurological disorders.
Smiles
ClC1=CC=CC(C(F)(F)COC2=NC=C(C(NC3(C4=CN=CC=N4)CC3)=O)N=C2)=C1
Molecular Formula
C20H16ClF2N5O2
Molecular Weight
431.823
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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