Products for Research Use Only
RegisterLogin

CB1R Allosteric modulator 5

CAT: 0804-HY-172587-01Size: 5 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0804-HY-172587-01Size:5 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
CB1R Allosteric modulator 5 (compound 3) is a selective, and blood-brain barrier (BBB) permeable Cannabinoid receptor type 1 allosteric modulator with a pIC50 of 6.89. CB1R Allosteric modulator 5 attenuates both cocaine-seeking behavior specific to cue-induced reinstatement and cocaine-induced behavioral sensitization without altering locomotor activity[1].
CAS Number
3019958-44-9
UNSPSC
12352005
Target
Cannabinoid Receptor
Related Pathways
GPCR/G Protein; Neuronal Signaling
Field of Research
Neurological Disease
Purity
98.35
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
O=C1C(NC2=CC=C(Cl)C=C2)=C(NCCC3=CC(Cl)=CC=C3)C1=O
Molecular Formula
C18H14Cl2N2O2
Molecular Weight
361.22
References & Citations
[1]Nguyen T, et al. Development of Squaramides as Allosteric Modulators of the CB1 Receptor: Synthesis, Computational Studies, Biological Characterization, and Effects against Cocaine-Induced Behavioral Sensitization and Reinstatement in Rats. J Med Chem. 2025 Apr 24;68 (8) :8694-8712.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported

Related Products

CatalogName
HY-150056-01CB1R Allosteric modulator 3
HY-147558CB1R Allosteric modulator 1
HY-150057CB1R Allosteric modulator 4
HY-147559CB1R Allosteric modulator 2
HY-W837864-01PDK1 allosteric modulator 1
HY-168494GluN2A Allosteric modulator 1
HY-155967CB1R/AMPK modulator 1
HY-161363ERK2 allosteric-IN-1
HY-176974DRP1 Allosteric-IN-2
HY-176975DRP1 Allosteric-IN-3

Alternative Products

CatalogName
C8475-5CB1R Allosteric modulator 3
T207547-01CB1R Allosteric modulator 5
GTR19187182-01CB1R Allosteric modulator 4
T62016-01CB1R Allosteric modulator 1
GTR19187280-01CB1R Allosteric modulator 2
T205030-01GluN2A Allosteric modulator 1
MBS5821310CB1R/AMPK modulator 1
MBS8005711-01Positive Allosteric Modulator of GABAA Receptors
TBI3937-10MGML382, MRGPRX1 positive allosteric modulator
TBI3489-25MGAllopregnanolone, GABA-A positive allosteric modulator

Popular Products