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MGluR2 modulator 4

CAT: 0804-HY-147530Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-147530Size:1 Each
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Description
MGluR2 modulator 4 (compound 47) is a potent mGluR2 positive allosteric modulator with an EC50 value of 0.8 μM. mGluR2 modulator 4 can be used for researching antipsychotic[1].
CAS Number
2582758-47-0
UNSPSC
12352005
Target
MGluR
Type
Reference compound
Related Pathways
GPCR/G Protein; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/mglur2-modulator-4.html
Solubility
10 mM in DMSO
Smiles
BrC1=CC=C(C=C1)CCN2CCN3C4=CC=CC=C4N=C3C2
Molecular Formula
C18H18BrN3
Molecular Weight
356.26
References & Citations
[1]Szabó G, et al. Discovery of dihydropyrazino-benzimidazole derivatives as metabotropic glutamate receptor-2 (mGluR2) positive allosteric modulators (PAMs) . Eur J Med Chem. 2020;186:111881.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
MGluR2

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