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MGluR2 modulator 2

CAT: 0804-HY-147528Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-147528Size:1 Each
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Description
MGluR2 modulator 2 (compound 2) is a potent, selective and orally bioavailable mGluR2 positive allosteric modulator with an EC50 value of 0.13 μM. mGluR2 modulator 2 can be used for researching antipsychotic[1].
CAS Number
1004614-86-1
UNSPSC
12352005
Target
MGluR
Type
Reference compound
Related Pathways
GPCR/G Protein; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/mglur2-modulator-2.html
Solubility
10 mM in DMSO
Smiles
CN1C2=CC=CC=C2N=C1CN3CCC(CC3)C4=CC=CC=C4F
Molecular Formula
C20H22FN3
Molecular Weight
323.41
References & Citations
[1]Szabó G, et al. Discovery of dihydropyrazino-benzimidazole derivatives as metabotropic glutamate receptor-2 (mGluR2) positive allosteric modulators (PAMs) . Eur J Med Chem. 2020;186:111881.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
MGluR2

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