CXCR4 modulator-2

CXCR4 modulator-2

• CAS Number: 2488943-55-9
• UNSPSC Description: CXCR4 modulator-2 (compound Z7R) is a highly potent CXCR4 modulator with an IC50 value of 1.25 nM. CXCR4 modulator-2 has acceptable stability (t1/2 = 77.1 min) in mouse serum and exhibits anti-inflammatory activity in mouse edema model[1].
• Target Antigen: CXCR
• Type: Reference compound
• Related Pathways: GPCR/G Protein;Immunology/Inflammation
• Applications: COVID-19-immunoregulation
• Field of Research: Inflammation/Immunology
• Assay Protocol: https://www.medchemexpress.com/cxcr4-modulator-2.html
• Solubility: 10 mM in DMSO
• Smiles: O=C(NC1CCN(C(CCN2C=CC3=C2C=NC=C3)=O)CC1)[C@H](N)CCCNC(N)=N
• Molecular Weight: 428.53
• References & Citations: [1]Oum YH, et al. Discovery of novel aminopiperidinyl amide CXCR4 modulators through virtual screening and rational drug design. Eur J Med Chem. 2020;201:112479.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported