CXCR4 modulator-2

• Description:

  CXCR4 modulator-2 (compound Z7R) is a highly potent CXCR4 modulator with an IC50 value of 1.25 nM. CXCR4 modulator-2 has acceptable stability (t1/2 = 77.1 min) in mouse serum and exhibits anti-inflammatory activity in mouse edema model[1].

• UNSPSC:

  12352005

• Target:

  CXCR

• Type:

  Reference compound

• Related Pathways:

  GPCR/G Protein; Immunology/Inflammation

• Applications:

  COVID-19-immunoregulation

• Field of Research:

  Inflammation/Immunology

• Assay Protocol:

  https://www.medchemexpress.com/cxcr4-modulator-2.html

• Solubility:

  10 mM in DMSO

• Smiles:

  O=C (NC1CCN (C (CCN2C=CC3=C2C=NC=C3) =O) CC1) [C@@H] (N) CCCNC (N) =N

• Molecular Formula:

  C21H32N8O2

• Molecular Weight:

  428.53

• References & Citations:

  [1]Oum YH, et al. Discovery of novel aminopiperidinyl amide CXCR4 modulators through virtual screening and rational drug design. Eur J Med Chem. 2020;201:112479.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• Isoform:

  CXCR4

• CAS Number:

  2554877-43-7