CXCR4 modulator-2

• Description :

  CXCR4 modulator-2 (compound Z7R) is a highly potent CXCR4 modulator with an IC50 value of 1.25 nM. CXCR4 modulator-2 has acceptable stability (t1/2 = 77.1 min) in mouse serum and exhibits anti-inflammatory activity in mouse edema model[1].

• UNSPSC :

  12352005

• Target :

  CXCR

• Type :

  Reference compound

• Related Pathways :

  GPCR/G Protein; Immunology/Inflammation

• Applications :

  COVID-19-immunoregulation

• Field of Research :

  Inflammation/Immunology

• Assay Protocol :

  https://www.medchemexpress.com/cxcr4-modulator-2.html

• Solubility :

  10 mM in DMSO

• Smiles :

  O=C(NC1CCN(C(CCN2C=CC3=C2C=NC=C3)=O)CC1)[C@@H](N)CCCNC(N)=N

• Molecular Formula :

  C21H32N8O2

• Molecular Weight :

  428.53

• References & Citations :

  [1]Oum YH, et al. Discovery of novel aminopiperidinyl amide CXCR4 modulators through virtual screening and rational drug design. Eur J Med Chem. 2020;201:112479.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• Isoform :

  CXCR4

• CAS Number :

  [2554877-43-7]