TRβ agonist 2

• Description :

  TRβ agonist 2 (Compound 1) is a potent agonist of TRβ. TRβ agonist 2 reduces lipid accumulation in HepG2 and promote lipolysis with comparable effects. TRβ agonist 2 is a new potential TRβ-selective thyromimetics[1].

• UNSPSC :

  12352005

• Target :

  Thyroid Hormone Receptor

• Type :

  Reference compound

• Related Pathways :

  Vitamin D Related/Nuclear Receptor

• Applications :

  Metabolism-sugar/lipid metabolism

• Field of Research :

  Metabolic Disease

• Assay Protocol :

  https://www.medchemexpress.com/trβ-agonist-2.html

• Solubility :

  10 mM in DMSO

• Smiles :

  CC(NC1=C(C=C(C=C1)CC2=C(C=C(C=C2C)OCC(O)=O)C)C(C)C)=O

• Molecular Formula :

  C22H27NO4

• Molecular Weight :

  369.45

• References & Citations :

  [1]Runfola M, et al. Design, synthesis and biological evaluation of novel TRβ selective agonists sustained by ADME-toxicity analysis. Eur J Med Chem. 2020 Feb 15;188:112006.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• CAS Number :

  [2411099-30-2]