TRβ agonist 3

• Description :

  TRβ agonist 3 (Compound 3) is a potent agonist of TRβ. TRβ agonist 3 reduces lipid accumulation in HepG2 and promote lipolysis with comparable effects. TRβ agonist 3 is a new potential TRβ-selective thyromimetics[1].

• UNSPSC :

  12352005

• Target :

  Thyroid Hormone Receptor

• Type :

  Reference compound

• Related Pathways :

  Vitamin D Related/Nuclear Receptor

• Applications :

  Metabolism-sugar/lipid metabolism

• Field of Research :

  Metabolic Disease

• Assay Protocol :

  https://www.medchemexpress.com/trβ-agonist-3.html

• Solubility :

  10 mM in DMSO

• Smiles :

  CC1=CC(OCC(O)=O)=CC(C)=C1CC2=CC(C(C)C)=C(C=C2)N

• Molecular Formula :

  C20H25NO3

• Molecular Weight :

  327.42

• References & Citations :

  [1]Runfola M, et al. Design, synthesis and biological evaluation of novel TRβ selective agonists sustained by ADME-toxicity analysis. Eur J Med Chem. 2020 Feb 15;188:112006.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• CAS Number :

  [2411099-46-0]