STAT3 degrader-1

STAT3 degrader-1

• CAS Number: 2497585-16-5
• UNSPSC Description: STAT3 degrader-1 (compound 295) is a potent STAT3 degrader. STAT3 degrader-1 can be used for researching anticancer[1]. STAT3 degrader-1 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
• Target Antigen: STAT
• Type: Reference compound
• Related Pathways: JAK/STAT Signaling;Stem Cell/Wnt
• Applications: Cancer-Kinase/protease
• Field of Research: Cancer
• Assay Protocol: https://www.medchemexpress.com/stat3-degrader-1.html
• Solubility: 10 mM in DMSO
• Smiles: FC(C=C1)=CC=C1C[C@H](NC([C@H](CCC(N)=O)NC([C@H]2N3[C@](CCN(C[C@@H](C3=O)NC(C4=CC5=CC(C(F)(F)P(O)(O)=O)=CC=C5S4)=O)CC(F)F)([H])CC2)=O)=O)C(N(CC6)CCC6CCC#CC7=C8C(C(N(C9C(NC(CC9)=O)=O)C8)=O)=CC=C7)=O
• Molecular Weight: 1236.20
• References & Citations: [1]Shaomeng Wang. Small molecule degraders of stat3. WO2020198435A1 (compound 295)
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported