STAT3 degrader-1

• UNSPSC Description:

  STAT3 degrader-1 (compound 295) is a potent STAT3 degrader. STAT3 degrader-1 can be used for researching anticancer[1]. STAT3 degrader-1 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

• Target Antigen:

  STAT

• Type:

  Reference compound

• Related Pathways:

  JAK/STAT Signaling;Stem Cell/Wnt

• Applications:

  Cancer-Kinase/protease

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/stat3-degrader-1.html

• Solubility:

  10 mM in DMSO

• Smiles:

  FC(C=C1)=CC=C1C[C@H](NC([C@H](CCC(N)=O)NC([C@H]2N3[C@](CCN(C[C@@H](C3=O)NC(C4=CC5=CC(C(F)(F)P(O)(O)=O)=CC=C5S4)=O)CC(F)F)([H])CC2)=O)=O)C(N(CC6)CCC6CCC#CC7=C8C(C(N(C9C(NC(CC9)=O)=O)C8)=O)=CC=C7)=O

• Molecular Weight:

  1236.20

• References & Citations:

  [1]Shaomeng Wang. Small molecule degraders of stat3. WO2020198435A1 (compound 295)

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  2497585-16-5