STAT3 HiBiT degrader 1

• UNSPSC Description:

  STAT3 HiBiT degrader 1 is a STAT3 HiBiT degrader with a DC50 of less than 0.05 μM in A549 cells[1].

• Target Antigen:

  STAT

• Type:

  Reference compound

• Related Pathways:

  JAK/STAT Signaling;Stem Cell/Wnt

• Field of Research:

  Cancer; Infection; Inflammation/Immunology

• Assay Protocol:

  https://www.medchemexpress.com/stat3-hibit-degrader-1.html

• Smiles:

  FC(F)(P(O)(O)=O)C1=CC(C=C(C(N[C@H]2CN(C(OC)=O)CC[C@@H]3N([C@H](C(N[C@@H](CCC(N)=O)C(N[C@H](C(N4CCC(CCC#CC5=CC(N(C)C(N6C7C(NC(CC7)=O)=O)=O)=C6C=C5)CC4)=O)CC8=CC=C(F)C(F)=C8)=O)=O)CC3)C2=O)=O)S9)=C9C=C1

• Molecular Weight:

  1263.21

• References & Citations:

  [1]Bin Yang, et al. Stat degraders and uses thereof. US. US20240293423A1. 2021.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  2767166-30-1