Tubulin polymerization-IN-10

Tubulin polymerization-IN-10

• CAS Number: 2238784-19-3
• UNSPSC Description: Tubulin polymerization-IN-10 is a potent tubulin polymerization inhibitor with an IC50 of 4.25±0.75 μM. Tubulin polymerization-IN-10 has anti-tumor effects[1].
• Target Antigen: Microtubule/Tubulin
• Type: Reference compound
• Related Pathways: Cell Cycle/DNA Damage;Cytoskeleton
• Applications: Cancer-programmed cell death
• Field of Research: Cancer
• Assay Protocol: https://www.medchemexpress.com/tubulin-polymerization-in-10.html
• Solubility: 10 mM in DMSO
• Smiles: NC1=CC(/C=C/S(=O)(C2=CC(OC)=C(OC)C(OC)=C2)=O)=CC=C1OC
• Molecular Weight: 379.43
• References & Citations: [1]Huajian Zhu, et al. Design, synthesis and biological evaluation of vinyl selenone derivatives as novel microtubule polymerization inhibitors. Eur J Med Chem . 2020 Dec 1;207:112716.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported