Tubulin polymerization-IN-50
CAT:
804-HY-155314
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Tubulin polymerization-IN-50
- CAS Number: 2998928-21-3
- UNSPSC Description: Tubulin polymerization-IN-50 (compound 7n) is a inhibitor of tubulin polymerization, with the IC50 of 5.05 μM in SK-Mel-28 cells. Tubulin polymerization-IN-50 induces the cell cycle arrest in the G2/M phase[1].
- Target Antigen: Microtubule/Tubulin
- Type: Reference compound
- Related Pathways: Cell Cycle/DNA Damage;Cytoskeleton
- Applications: Cancer-programmed cell death
- Field of Research: Cancer
- Assay Protocol: https://www.medchemexpress.com/tubulin-polymerization-in-50.html
- Solubility: 10 mM in DMSO
- Smiles: COC1=CC(C2=NC3=C(N2)C=CC(F)=C3)=CC=C1OCC(N4CCC5=C4C=CC=C5)=O
- Molecular Weight: 417.43
- References & Citations: [1]Laxmikeshav K et al. Benzimidazole derivatives as tubulin polymerization inhibitors: Design, synthesis and in vitro cytotoxicity studies [published online ahead of print, 2023 Oct 3]. Bioorg Med Chem Lett. 2023;96:129494.
- Shipping Conditions: Room temperature
- Clinical Information: No Development Reported