Tubulin polymerization-IN-53
CAT:
804-HY-155350
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
Tubulin polymerization-IN-53
- UNSPSC Description: Tubulin polymerization-IN-53 (compound 4b) is an inhibitor of β-tubulin polymerization. Tubulin polymerization-IN-53 can arrest the cell cycle at the G2/M stage. Tubulin polymerization-IN-53 has antiproliferative efficacy against the MDA-MB-231 cell line with an IC50 value of 3.24 μM[1].
- Target Antigen: Microtubule/Tubulin
- Type: Reference compound
- Related Pathways: Cell Cycle/DNA Damage;Cytoskeleton
- Applications: Cancer-programmed cell death
- Field of Research: Others
- Assay Protocol: https://www.medchemexpress.com/tubulin-polymerization-in-53.html
- Solubility: 10 mM in DMSO
- Smiles: O=C(C1=CC(OC)=C(C(OC)=C1)OC)N/C(C(O)=O)=C\C2=CC=C(C=C2)Cl
- Molecular Weight: 391.80
- References & Citations: [1]Eman Fayad, et al. Novel Acrylate-Based Derivatives: Design, Synthesis, Antiproliferative Screening, and Docking Study as Potential Combretastatin Analogues. ACS Omega. 2023, 8,41.
- Shipping Conditions: Room temperature
- Clinical Information: No Development Reported