Tubulin polymerization-IN-3
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804-HY-145868
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Tubulin polymerization-IN-3
- UNSPSC Description: Tubulin polymerization-IN-3 (compound 4c) is a potent tubulin polymerization inhibitor, with an IC50 of 3.84 µM. Tubulin polymerization-IN-3 can induce apoptosis in colon cancer cells[1].
- Target Antigen: Apoptosis; Microtubule/Tubulin
- Type: Reference compound
- Related Pathways: Apoptosis;Cell Cycle/DNA Damage;Cytoskeleton
- Applications: Cancer-programmed cell death
- Field of Research: Cancer
- Assay Protocol: https://www.medchemexpress.com/tubulin-polymerization-in-3.html
- Solubility: 10 mM in DMSO
- Smiles: COC1=CC(C2=CC(C3C=CC(Cl)=CC3)=NC4=NC(N)=NN24)=CC(OC)=C1OC
- Molecular Weight: 413.86
- References & Citations: [1]Mohamed HS, et, al. Design, synthesis, biological assessment, and in-Silico studies of 1,2,4-triazolo[1,5-a]pyrimidine derivatives as tubulin polymerization inhibitors. Bioorg Chem. 2022 Apr;121:105687.
- Shipping Conditions: Room temperature
- Clinical Information: No Development Reported