NLRP3-IN-9

NLRP3-IN-9

• CAS Number: 2768759-64-2
• UNSPSC Description: NLRP3-IN-9 is a potent NLRP3 inhibitor. NLRP3-IN-9 inhibits IL-1β release. NLRP3-IN-9 reduces inflammation and mechanical hyperalgesia. NLRP3-IN-9 has the potential for the research of gout[1].
• Target Antigen: NOD-like Receptor (NLR)
• Type: Reference compound
• Related Pathways: Immunology/Inflammation
• Applications: COVID-19-immunoregulation
• Field of Research: Inflammation/Immunology
• Assay Protocol: https://www.medchemexpress.com/nlrp3-in-9.html
• Solubility: 10 mM in DMSO
• Smiles: O=C(N([Na])S(C1=CC(C(C)(O)C)=CO1)(=O)=O)NC2=CC(C)=CC(C)=C2
• Molecular Weight: 374.39
• References & Citations: [1]Narros-Fernández P, et al. Synthesis and Pharmacological Evaluation of New N-Sulfonylureas as NLRP3 Inflammasome Inhibitors: Identification of a Hit Compound to Treat Gout. J Med Chem. 2022 Apr 28;65(8):6250-6260.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported