NLRP3-IN-6

NLRP3-IN-6

• UNSPSC Description: NLRP3-IN-6 (Compound 34) is a selective NLRP3 inflammasome inhibitor[1].
• Target Antigen: NOD-like Receptor (NLR)
• Type: Reference compound
• Related Pathways: Immunology/Inflammation
• Applications: COVID-19-immunoregulation
• Field of Research: Inflammation/Immunology; Neurological Disease
• Assay Protocol: https://www.medchemexpress.com/nlrp3-in-6.html
• Solubility: 10 mM in DMSO
• Smiles: O=C(/C(SC1=S)=C/C2=CC=C(C=C2)S(N)(=O)=O)N1CC3=CC(Cl)=CC=C3OC
• Molecular Weight: 454.97
• References & Citations: [1]Zuo D, et al. Design and synthesis of an N-benzyl 5-(4-sulfamoylbenzylidene-2-thioxothiazolidin-4-one scaffold as a novel NLRP3 inflammasome inhibitor. Bioorg Med Chem Lett. 2022 Jun 1;65:128693.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported