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NLRP3-IN-9

CAT: 0931-T28178-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0931-T28178-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
88039-46-7
Target
NOD, NOD-like Receptor (NLR)
Related Pathways
Immunology/Inflammation, NF-κB
Purity
0.9964
Bioactivity
NLRP3-IN-9 (INF-4E) is an inhibitor of NLRP3 ATPase and caspase-1. NLRP3-IN-9 acts by irreversibly trapping thiol nucleophiles, which prevents both ATP- and nigericin-triggered pyroptosis of human THP-1 cells in a time- and concentration-dependent manner.
Smiles
CCOC(=O)C(=C)C(O)c1ccccc1Cl
Molecular Formula
C12H13ClO3
Molecular Weight
240.68
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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