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MAO-B-IN-7

CAT: 0804-HY-146762Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-146762Size:1 Each
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Description
MAO-B-IN-7 is a potent and blood-brain barrier permeable MAO-B and AChE inhibitor with IC50s of 41 nM, 87 nM and 0.3 μM for human AChE, electric eel AChE and MAO-B, respectively. MAO-B-IN-7 can effectively alleviate oxidative stress and neuroinflammatory damage[1].
CAS Number
2851012-65-0
UNSPSC
12352005
Target
Cholinesterase (ChE) ; Monoamine Oxidase; Reactive Oxygen Species (ROS)
Type
Reference compound
Related Pathways
Immunology/Inflammation; Metabolic Enzyme/Protease; Neuronal Signaling; NF-κB
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology; Neurological Disease
Assay Protocol
https://www.medchemexpress.com/mao-b-in-7.html
Solubility
10 mM in DMSO
Smiles
CCCCC1OC(C2=CC(OCC3=CC(O)=C(C=C3)CN4CCCCC4)=CC=C21)=O
Molecular Formula
C25H31NO4
Molecular Weight
409.52
References & Citations
[1]Liu Z, et al. Discovery of novel 3-butyl-6-benzyloxyphthalide Mannich base derivatives as multifunctional agents against Alzheimer's disease. Bioorg Med Chem.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
AChE; MAO-B

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