TRK-IN-17

• CAS Number:

  2409544-80-3

• UNSPSC Description:

  TRK-IN-17 is a potent inhibitor of TRK. Tropomyosin-related kinases (Trks) are a family of receptor tyrosine kinases activated by neurotrophins, a group of soluble growth factors including Nerve Growth Factor (NGF), Brain-Derived Neurotrophic Factor (BDNF) and Neurotrophin-3 (NT-3) and Neurotrophin-4/5 (NT-4/5). TRK-IN-17 has the potential for the research of cancer diseases (extracted from patent WO2021148807A1, compound 3)[1].

• Target Antigen:

  Trk Receptor

• Type:

  Reference compound

• Related Pathways:

  Neuronal Signaling;Protein Tyrosine Kinase/RTK

• Applications:

  Cancer-Kinase/protease

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/trk-in-17.html

• Solubility:

  10 mM in DMSO

• Smiles:

  CCN/C(C1=CN=C2C=CC(N3C[C@H](C[C@@H]3C4=CC(F)=CC(SC)=C4)F)=NN12)=N\C#N

• Molecular Weight:

  441.50

• References & Citations:

  [1]Nicola ROBAS, et al. Pharmaceutical compositions and their uses. Patent WO2021148807A1.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported