TRK-IN-17

TRK-IN-17

• CAS Number: 2409544-80-3
• UNSPSC Description: TRK-IN-17 is a potent inhibitor of TRK. Tropomyosin-related kinases (Trks) are a family of receptor tyrosine kinases activated by neurotrophins, a group of soluble growth factors including Nerve Growth Factor (NGF), Brain-Derived Neurotrophic Factor (BDNF) and Neurotrophin-3 (NT-3) and Neurotrophin-4/5 (NT-4/5). TRK-IN-17 has the potential for the research of cancer diseases (extracted from patent WO2021148807A1, compound 3)[1].
• Target Antigen: Trk Receptor
• Type: Reference compound
• Related Pathways: Neuronal Signaling;Protein Tyrosine Kinase/RTK
• Applications: Cancer-Kinase/protease
• Field of Research: Cancer
• Assay Protocol: https://www.medchemexpress.com/trk-in-17.html
• Solubility: 10 mM in DMSO
• Smiles: CCN/C(C1=CN=C2C=CC(N3C[C@H](C[C@@H]3C4=CC(F)=CC(SC)=C4)F)=NN12)=N\C#N
• Molecular Weight: 441.50
• References & Citations: [1]Nicola ROBAS, et al. Pharmaceutical compositions and their uses. Patent WO2021148807A1.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported