COX-2-IN-12

COX-2-IN-12

• CAS Number: 2986222-50-6
• UNSPSC Description: COX-2-IN-12 (compound 3b) is a potent and selective inhibitor of COX-2 with an IC50 of 19.98 μM. COX-2-IN-12 is an anti-inflammatory agent. COX-2-IN-12 shows safety in-vivo acute toxicity study[1].
• Target Antigen: COX
• Type: Reference compound
• Related Pathways: Immunology/Inflammation
• Applications: COVID-19-immunoregulation
• Field of Research: Inflammation/Immunology
• Assay Protocol: https://www.medchemexpress.com/cox-2-in-12.html
• Solubility: 10 mM in DMSO
• Smiles: O=C1CCCCC1C2CC(N(C2=O)CC3=CC=CC=C3)=O
• Molecular Weight: 285.34
• References & Citations: [1]Jan MS, et al. Design, synthesis, in-vitro, in-vivo and in-silico studies of pyrrolidine-2,5-dione derivatives as multitarget anti-inflammatory agents. Eur J Med Chem. 2020;186:111863.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported